After around 10-12 years of using just MacOS and the occasional Linux, I finally got a Windows machine again, to use for some light gaming on Steam.
One of the things you get used from the world of Mac, for good or for bad, is the “natural” scrolling for the mouse. Unfortunately, in Windows 10, if you don’t have a touchpad, you don’t have the option in Settings.
I found this solution, using Windows Registry:
Use the Windows key + R keyboard shortcut to open the Run command.
Type regedit, and click OK to open the Registry.
Browse the following path:
Computer\HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\HID
Quick tip: On Windows 10, you can now copy and paste the path in the Registry’s address bar to quickly jump to the key destination.Expand the key (folder) that matches the VID ID of your mouse — for example, VID_0E0F&PID_0003&MI_01.
from WindowsCentral.com
There’s a little bit more than the steps above, so go to WindowsCentral for the full list of steps, in case you have this issue.